Megaman and Bass
Many players will recognize this by the Japanese title "Rockman and Forte". North American gamers did receive a port of the game on the Gameboy Advance although it wasn't up to the high standards of the Super Famicom version.
While the gameplay doesn't deviate too far from the tried and true Megaman formula, Megaman and Bass did add a few things. The most notable is that the player can choose to play as either Megaman or Bass both of which have different weapons and movements.
Certainly one of the better Super Famicom titles that didn't make it's way over here, every Megaman fan owes it to themselves to play this one.